Preview of Part of the Neuron Affected, Inhibitory or Excitatory Potential Changes and Ion Channels Affected by Psilocybin:
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Part of the Neuron Affected, Inhibitory or Excitatory Potential
Changes and Ion Channels Affected by Psilocybin


Psilocybin belongs to the classification of drugs called
hallucinogens. Hallucinogens typically act by stimulating
serotonin receptors at different times or for longer durations
than serotonin itself would (Kalat 2004). When psilocybin enters
the brain, the enzyme alkaline breaks down one of its phosphate
groups through hydrolysis. It then becomes psilocin, an even
stronger hallucinogen (Psilocybin 2003). It is particularly
potent due to the position of its hydroxyl group (Jacobs 1984).
Psilocin is a postsynaptic serotonin receptor agonist. In other
words, its similar structure allows it to mimic serotonin,
fitting into some types of serotonin receptors and producing the
same effect as endogenous serotonin (Merriam Webster 2003).
Specifically, psilocin activates the 5HT2A and 5HT1A receptors.
Stimulation of 5HT1 receptors is associated with an inhibitory
response while stimulation of the 5HT2 receptors is associated
with an excitatory r... [to view the full essay now, purchase below]

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